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Livres
Articles (27)
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1

Correction to Discovery of Small-Molecule Inhibitors Selectively Targeting the DNA-Binding Domain of the Human Androgen Receptor

Li, Huifang, Ban, Fuqiang, Dalal, Kush, Leblanc, Eric, Frewin, Kate, Ma, Dennis, Adomat, Hans, Rennie, Paul S., Cherkasov, Artem

Journal:

Journal of Medicinal Chemistry

Année:

2017

Langue:

english

Fichier:

PDF, 826 KB

english, 2017

2

RPA nucleic acid-binding properties of IFI16-HIN200

Hongyue Yan, Kush Dalal, Benjamin K. Hon, Philippe Youkharibache, Desmond Lau, Frederic Pio

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Année:

2008

Langue:

english

Fichier:

PDF, 1.67 MB

english, 2008

3

The SecY complex forms a channel capable of ionic discrimination

Dalal, Kush, Duong, Franck

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 940 KB

english, 2009

4

Nanodiscs unravel the interaction between the SecYEG channel and its cytosolic partner SecA

Alami, Meriem, Dalal, Kush, Lelj-Garolla, Barbara, Sligar, Stephen G, Duong, Franck

Journal:

The EMBO Journal

Année:

2007

Langue:

english

Fichier:

PDF, 463 KB

english, 2007

5

The SecY complex: conducting the orchestra of protein translocation

Kush Dalal, Franck Duong

Journal:

Trends in Cell Biology

Année:

2011

Langue:

english

Fichier:

PDF, 1.34 MB

english, 2011

6

Thermodynamics and stability of the PAAD/DAPIN/PYRIN domain of IFI-16

Kush Dalal, Frederic Pio

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 669 KB

english, 2006

7

Increasing Chloride Conductance Through the SecY Complex By Mutagenesis or Trivalent Cations

Bao, Huan, Dalal, Kush, Duong, Franck

Journal:

Biophysical Journal

Année:

2010

Langue:

english

Fichier:

PDF, 38 KB

english, 2010

8

Target selection of soluble protein complexes for structural proteomics studies

Weiping Shen, Steven Yun, Bonny Tam, Kush Dalal, Frederic F Pio

Journal:

Proteome Science

Année:

2005

Langue:

english

Fichier:

PDF, 1.91 MB

english, 2005

9

The maltose ABC transporter: Action of membrane lipids on the transporter stability, coupling and ATPase activity

Bao, Huan, Dalal, Kush, Wang, Victor, Rouiller, Isabelle, Duong, Franck

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Année:

2013

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2013

10

Discovery of Small-Molecule Inhibitors Selectively Targeting the DNA-Binding Domain of the Human Androgen Receptor

Li, Huifang, Ban, Fuqiang, Dalal, Kush, Leblanc, Eric, Frewin, Kate, Ma, Dennis, Adomat, Hans, Rennie, Paul S., Cherkasov, Artem

Journal:

Journal of Medicinal Chemistry

Année:

2014

Langue:

english

Fichier:

PDF, 3.70 MB

english, 2014

11

Selectively Targeting the DNA-binding Domain of the Androgen Receptor as a Prospective Therapy for Prostate Cancer

Dalal, Kush, Roshan-Moniri, Mani, Sharma, Aishwariya, Li, Huifang, Ban, Fuqiang, Hessein, Mohamed, Hsing, Michael, Singh, Kriti, LeBlanc, Eric, Dehm, Scott, Tomlinson Guns, Emma S., Cherkasov, Artem,

Journal:

Journal of Biological Chemistry

Année:

2014

Langue:

english

Fichier:

PDF, 3.14 MB

english, 2014

12

Selectively targeting the DNA-binding domain of the androgen receptor as a prospective therapy for prostate cancer.

Dalal, Kush, Roshan-Moniri, Mani, Sharma, Aishwariya, Li, Huifang, Ban, Fuqiang, Hessein, Mohamed, Hsing, Michael, Singh, Kriti, LeBlanc, Eric, Dehm, Scott, Tomlinson Guns, Emma S., Cherkasov, Artem,

Journal:

Journal of Biological Chemistry

Année:

2014

Langue:

english

Fichier:

PDF, 495 KB

english, 2014

13

Targeting Alternative Sites on the Androgen Receptor to Treat Castration-Resistant Prostate Cancer

Lallous, Nada, Dalal, Kush, Cherkasov, Artem, Rennie, Paul

Journal:

International Journal of Molecular Sciences

Année:

2013

Langue:

english

Fichier:

PDF, 1.67 MB

english, 2013

14

Selectively targeting the DNA-binding domain of the androgen receptor as a prospective therapy for prostate cancer.

Dalal, Kush, Roshan-Moniri, Mani, Sharma, Aishwariya, Li, Huifang, Ban, Fuqiang, Hassona, Mohamed D., Hsing, Michael, Singh, Kriti, LeBlanc, Eric, Dehm, Scott, Tomlinson Guns, Emma S., Cherkasov, Arte

Journal:

Journal of Biological Chemistry

Année:

2015

Fichier:

PDF, 35 KB

2015

15

Modulation of the SecY channel permeability by pore mutations and trivalent cations

Dalal, Kush, Bao, Huan, Duong, Franck

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 883 KB

english, 2010

16

MP62-01 TARGETING THE DNA BINDING DOMAIN OF THE ANDROGEN RECEPTOR: EFFICACY OF PROSTATE CANCER COMPOUND WITH NOVEL MECHANISM OF ACTION

Borgmann, Hendrik, Dalal, Kush, Beraldi, Eliana, Cherkasov, Artem, Rennie, Paul, Gleave, Martin

Journal:

The Journal of Urology

Année:

2016

Langue:

english

Fichier:

PDF, 35 KB

english, 2016

17

Sequential Action of MalE and Maltose Allows Coupling ATP Hydrolysis to Translocation in the MalFGK 2 Transporter

Bao, Huan, Dalal, Kush, Cytrynbaum, Eric, Duong, Franck

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 1.41 MB

english, 2015

18

Selectively targeting the DNA-binding domain of the androgen receptor as a prospective therapy for prostate cancer.

Dalal, Kush, Roshan-Moniri, Mani, Sharma, Aishwariya, Li, Huifang, Ban, Fuqiang, Hassona, Mohamed D., Hsing, Michael, Singh, Kriti, LeBlanc, Eric, Dehm, Scott, Tomlinson Guns, Emma S., Cherkasov, Arte

Journal:

Journal of Biological Chemistry

Année:

2017

Langue:

english

Fichier:

PDF, 97 KB

english, 2017

19

Best Practices of Computer-Aided Drug Discovery (CADD): Lessons Learned from the Development of a Preclinical Candidate for Prostate Cancer with a New Mechanism of Action

Ban, Fuqiang, Dalal, Kush, Li, Huifang, LeBlanc, Eric, Rennie, Paul S., Cherkasov, Artem

Journal:

Journal of Chemical Information and Modeling

Année:

2017

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2017

20

Bypassing drug-resistance mechanisms of prostate cancer with small-molecules that target androgen receptor chromatin interactions

Dalal, Kush, Che, Meixia, Que, Nanette S., Sharma, Aishwariya, Yang, Rendong, Lallous, Nada, Borgmann, Hendrik, Ozistanbullu, Deniz, Tse, Ronnie, Ban, Fuqiang, Li, Huifang, Tam, Kevin J., Roshan-Monir

Journal:

Molecular Cancer Therapeutics

Année:

2017

Langue:

english

Fichier:

PDF, 6.55 MB

english, 2017

21

Moving Towards Precision Urologic Oncology: Targeting Enzalutamide-resistant Prostate Cancer and Mutated Forms of the Androgen Receptor Using the Novel Inhibitor Darolutamide (ODM-201)

Borgmann, Hendrik, Lallous, Nada, Ozistanbullu, Deniz, Beraldi, Eliana, Paul, Naman, Dalal, Kush, Fazli, Ladan, Haferkamp, Axel, Lejeune, Pascale, Cherkasov, Artem, Gleave, Martin E.

Journal:

European Urology

Année:

2017

Langue:

english

Fichier:

PDF, 954 KB

english, 2017

22

Cheminformatics Driven Development of Novel Therapies for Drug Resistant Prostate Cancer

Ban, Fuqiang, Dalal, Kush, LeBlanc, Eric, Morin, Hélène, Rennie, Paul S., Cherkasov, Artem

Journal:

Molecular Informatics

Année:

2018

Langue:

english

Fichier:

PDF, 1.47 MB

english, 2018

23

Benzothiophenone Derivatives Targeting Mutant Forms of Estrogen Receptor-α in Hormone-Resistant Breast Cancers

Singh, Kriti, Munuganti, Ravi, Lallous, Nada, Dalal, Kush, Yoon, Ji, Sharma, Aishwariya, Yamazaki, Takeshi, Cherkasov, Artem, Rennie, Paul

Journal:

International Journal of Molecular Sciences

Année:

2018

Langue:

english

Fichier:

PDF, 5.15 MB

english, 2018

24

Small molecule-induced degradation of the full length and V7 truncated variant forms of human androgen receptor

Dalal, Kush, Morin, Helene, Ban, Fuqiang, Shepherd, Ashley, Fernandez, Michael, Tam, Kevin J., Li, Huifang, LeBlanc, Eric, Lack, Nathan, Prinz, Helge, Rennie, Paul S., Cherkasov, Artem

Journal:

European Journal of Medicinal Chemistry

Année:

2018

Fichier:

PDF, 7.01 MB

2018

25

Small molecule-induced degradation of the full length and V7 truncated variant forms of human androgen receptor

Dalal, Kush, Morin, Helene, Ban, Fuqiang, Shepherd, Ashley, Fernandez, Michael, Tam, Kevin J., Li, Huifang, LeBlanc, Eric, Lack, Nathan, Prinz, Helge, Rennie, Paul S., Cherkasov, Artem

Journal:

European Journal of Medicinal Chemistry

Année:

2018

Langue:

english

Fichier:

PDF, 7.01 MB

english, 2018

26

Selectively targeting the dimerization interface of human androgen receptor with small-molecules to treat castration-resistant prostate cancer

Dalal, Kush, Ban, Fuqiang, Li, Huifang, Morin, Hélène, Roshan-Moniri, Mani, Tam, Kevin J., Shepherd, Ashley, Sharma, Aishwariya, Peacock, James, Carlson, Michael L., LeBlanc, Eric, Perez, Carl, Duong,

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 4.35 MB

english, 2018

27

Targeting Semaphorin 3C in Prostate Cancer with Small Molecules

Lee, Chung C W, Munuganti, Ravi Shashi Nayana, Peacock, James W, Dalal, Kush, Jiao, Ivy Z F, Shepherd, Ashley, Liu, Liangliang, Tam, Kevin J, Sedgwick, Colin G, Bhasin, Satyam, Lee, Kevin C K, Gooding

Journal:

Journal of the Endocrine Society

Année:

2018

Langue:

english

Fichier:

PDF, 1.07 MB

english, 2018